Jonny Bowden, Ph.D., C.N.S.
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 Group one got grapefruit capsules before meals, group two got grapefruit juice, group three got half a grapefruit, and group four got a placebo (nothing). The placebo group lost about l/i of a pound, the grapefruit capsule group lost 1.1 pounds, the grapefruit juice group lost 1.3, and the real grapefruit folks lost 1.5. Overall, only the fresh grapefruit group reached "statistical significance," but among those with metabolic syndrome, all three grapefruit groups lost significantly more weight. Insulin resistance was improved in everyone. |
Jack Challem
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 People taking capsules were given a small amount of apple juice to match the calories of the grapefruit and the grapefruit juice. In every other respect, the subjects were encouraged to follow their usual eating habits.
By the end of the study, people eating the fresh grapefruit lost an average of 3.6 pounds, those drinking grapefruit juice lost 3.3 pounds, and those taking grapefruit capsules lost 2.4 pounds. In contrast, subjects taking the placebos lost only one-half pound. |
C. W. Randolph, M.D.
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 Saturated Fat 0 g - Cholesterol 0 mg - Sodium 1 35 mg - Total Carbohydrate 39 g Dietary Fiber 9 g - Sugars 6 g - Protein 1 1 g - Calcium 6% DV
Grilled Fish with Citrus Marinade
Vi cup extra-virgin olive oil
2 tablespoons grapefruit juice
3 tablespoons lime juice Salt and pepper to taste
4 (6-ounce) fish filets
Combine olive oil, grapefruit juice, lime juice, salt, and pepper. Pour over fish and marinate in refrigerateor for 2 or more hours. Grill and serve. Makes 4 servings.
NUTRITION FACTS
Amount Per Serving: Calories 200 - Calories from Fat 60 - Total Fat 6 g - Saturated Fat 1. |
Jack Challem
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| People taking capsules were given a small amount of apple juice to match the calories of the grapefruit and the grapefruit juice. In every other respect, the subjects were encouraged to follow their usual eating habits.
By the end of the study, people eating the fresh grapefruit lost an average of 3.6 pounds, those drinking grapefruit juice lost 3.3 pounds, and those taking grapefruit capsules lost 2.4 pounds. In contrast, subjects taking the placebos lost only one-half pound. |
David W. Grotto, RD, LDN
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 PERIODONTAL DISEASE: A study found that bleeding associated with periodontitis was significantly reduced after drinking grapefruit juice. The researchers attribute the amazing results to the vitamin C content of grapefruit juice, known to help wound and tissue repair.
HEART HEALTH: Researchers studied the effect of eating one grapefruit a day on fifty-seven patients who had bypass surgery. Those who consumed one red grapefruit a day for thirty days showed decreases in total cholesterol, LDL ("bad") cholesterol, and triglycerides. |
Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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 Drinking grapefruit juice has been linked to an increased risk of kidney stones in two large studies.31'32 Whether grapefruit juice actually causes kidney stone recurrence or is merely associated with something else that increases risks remains unclear; some doctors suggest that people with a history of stones should restrict grapefruit juice intake until more is known.
Bran, a rich source of insoluble fiber (page 512), reduces the absorption of calcium (page 483), which in turn causes urinary calcium to fall. |
Bill Sardi
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 Drug Safety 28:677-94, 2005] The same problem is documented when taking grapefruit juice with a blood pressure pill. The blood pressure drug may work too well, resulting in an inordinate drop in blood pressure and dizziness experienced by the patient. The FDA hasn't banned grapefruit juice; it just instructs users of drugs to avoid simultaneous consumption of grapefruit with certain drugs. Chaparral may be unfairly characterized as a liver toxin when it is no more harmful than grapefruit. This may explain the inconsistent reports of liver toxicity. |
Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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| Whether grapefruit juice actually causes kidney stone recurrence or is merely associated with something else that increases risks remains unclear; some doctors suggest that people with a history of stones should restrict grapefruit juice intake until more is known.
Bran, a rich source of insoluble fiber (page 512), reduces the absorption of calcium (page 483), which in turn causes urinary calcium to fall.33 In one trial, risk of forming kidney stones was significantly reduced simply by adding one-half ounce of rice bran per day to the diet. |
Jonny Bowden, Ph.D., C.N.S.
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| In a controlled study involving forty-nine smokers, researchers at the University of Hawaii found that drinking three 6-ounce glasses of grapefruit juice a day reduced the activity of a liver enzyme called CYP1A2 that is thought to activate cancer-causing chemicals found in tobacco smoke. It's reasonable to think that might be helpful for nonsmokers as well, since reducing the activity of an enzyme that activates cancer-causing chemicals is a good thing no matter where the chemicals come from! |
| Don't take grapefruit juice with medicine. Why? It causes the medicine to stay in the bloodstream longer, which in some cases can boost the amount in your system to a dangerous high. |
Marshall Editions
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 Avoid carbonated beverages that contain phosphates as these have been associated with the development of stones. grapefruit juice should also be avoided as it has been linked to the formation of kidney stones in some studies. Avoiding calcium is generally thought to be unhelpful, and some doctors even advocate calcium supplementation as a preventive measure. Generally, avoiding a high-protein diet, particularly animal protein, is wise. |
Bill Sardi
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| The FDA hasn't banned grapefruit juice; it just instructs users of drugs to avoid simultaneous consumption of grapefruit with certain drugs. Chaparral may be unfairly characterized as a liver toxin when it is no more harmful than grapefruit. This may explain the inconsistent reports of liver toxicity. A 78-page report issued by the Institute of Medicine and National Research Council on chaparral in 2004 explains many of the promises and problems associated with chaparral., but it is probably too lengthy a document for cancer patients to wade through. |
Bottom Line Health
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| Wait one to two hours after taking any of these drugs before having grapefruit or grapefruit juice.
•Bran muffins, whole-grain cereals and other high-fiber foods. Fiber slows the absorption of penicillin, ampicillin and other antibiotics. In some cases, it binds to drugs in the intestine and prevents most of the active ingredient from entering the blood.
Warning: Fiber can also block the absorption of the heart drug digoxin (Lanoxin). Don't consume high-fiber foods or fiber supplements within two hours of taking this drug.
•Dairy. |
Andreas Moritz
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 If you cannot tolerate grapefruit juice or if it tends to make you nauseated, you may use equal amounts of freshly squeezed lemon and orange juice instead. The effect is the same with either choice.
Preparation
> Drink 1 container (32 oz.) of packaged or freshly prepared apple juice (or see other options below) per day for a period of six days: (You may drink more than that if it feels comfortable to do so.) The malic acid in the apple juice softens the gallstones and makes their passage through the bile ducts smooth and easy. The apple juice has a strong cleansing effect. |
| Reduce
Almond drink Almond milk Caffeinated beverages
Grape juice Mango juice Vegetable broth, salted
Lassi
Avoid
Alcohol Banana shake Carbonated beverages Chocolate beverages Coconut milk
Cold beverages grapefruit juice Lemonade Licorice tea Milk shakes
Orange juice Papaya juice Sour beverages Tomato juice Sports drinks
Important for all body types
In the above food charts I have omitted beef, pork, poultry, fish, eggs and similar foods because they can create major imbalances in all three body types. (See the section on vegetarianism later in this chapter. |
Jonny Bowden, Ph.D., C.N.S.
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| Multiple studies have also suggested that grapefruit juice raises the risk of kidney stones.
C* rapes
Grapes are one of my favorite desserts, but my secret is this: I freeze them. Don't knock it till you try it. They taste like little balls of sherbet, and they're the perfect munchy finger food for watching late-night reruns of Seinfeld.
Grapes are a whole pharmacy of healthful nutrients, many of which are potentially life extending. Take resveratrol. |
Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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| Whether grapefruit juice actually causes kidney stone recurrence or is merely associated with something else that increases risks remains unclear; some doctors suggest that people with a history of stones should restrict grapefruit juice intake until more is known.
Bran, a rich source of insoluble fiber (page 512), reduces the absorption of calcium (page 483), which in turn causes urinary calcium to fall.33 In one trial, risk of forming kidney stones was significantly reduced simply by adding one-half ounce of rice bran per day to the diet. |
Jonny Bowden, Ph.D., C.N.S.
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 And research shows that grapefruit juice raises the risk of stones by as much as 44 percent, so if you're prone to stone formation, avoid it. Ditto with salt. In one review paper in the journal Nutrition Reviews, researchers theorized that stone formers may be more sensitive to salt than non-stone formers and that for those folks, a reduced intake of salt may decrease the risk of kidney stones.
Conventional treatment advocates pain relief medications, such as nonsteroidal antiinflammatory drugs (such as ibuprofen or aspirin) or narcotics like Percocet. |
| Avoid grapefruit juice.
If you need more data to put the urban legend about restricting calcium to rest, consider this: The largest prospective epidemiological study ever published on calcium and kidney stones (New England Journal of Medicine) concluded that high calcium intake is associated with a decreased risk of symptomatic kidney stones. The 1993 study, which followed more than 45,000 men, found that those who consumed less than 850 mg of calcium per day were at an increased risk for kidney stones. |
Caldwell B. Esselstyn, Jr., M.D.
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 A bit of apple juice, cider, or fresh orange or grapefruit juice (include the fruit sections) is delicious in place of milk. But you can also eat your cereal with milk, oat milk, almond milk, or nonfat soy milk. And cereals are far from the only breakfast option. Pancakes made from whole-wheat flour (containing no eggs and no oil) are really good! Toasted whole-grain bread topped with summer-ripe, fresh peaches heads my own list of outrageously delicious breakfasts. You should also try sliced bananas, ripe mangos, strawberries, or other favorite fruits on toast. Think outside the box. |
Richard Beliveau, Ph.D. and Denis Gingras, Ph.D.
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 The interaction of citrus fruits with these systems is nicely illustrated by the surprising effect that grapefruit juice can have on the metabolism of certain drugs. In the course of a study intended to determine the impact of alcohol on the effectiveness of a commonly prescribed cardiac arrhythmia medication, researchers accidentally discovered that the grapefruit juice used to mask the taste of the alcohol was responsible for doubling the amount of medication in the bloodstream, and increasing the number and severity of side effects. |
David W. Grotto, RD, LDN
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| The researchers attribute the amazing results to the vitamin C content of grapefruit juice, known to help wound and tissue repair.
HEART HEALTH: Researchers studied the effect of eating one grapefruit a day on fifty-seven patients who had bypass surgery. Those who consumed one red grapefruit a day for thirty days showed decreases in total cholesterol, LDL ("bad") cholesterol, and triglycerides. |
| Check with your doctor, a pharmacist, or a registered dietitian to see if grapefruit juice is right for you.
Tips on Using Grapefruit
SELECTION AND STORAGE:
• There are two main varieties of grapefruit, white and pink/red, that can be found year-round.
• Choose firm and heavy grapefruits for their size. Avoid those that appear to have water-soaked areas or have an overly soft spot at the stem. Watch for signs of dehydration and skin collapse at the stem. |
David Heber, M.D., Ph.D.
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 The fact that drinking grapefruit juice can affect how your body breaks down the most widely prescribed cholesterol-lowering drugs proves this point. When taken at usual doses, the blood levels of the drug are found to be twice as high after drinking double-strength grapefruit juice for three days. There is an enzyme on the surface of the small intestine whose production is inhibited by chemicals in the grapefruit juice. This type of interaction of chemicals in grapefruit juice with your genes is an example of how diet can powerfully affect the body's enzyme systems. |
Paula Begoun and Bryan Barron
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 The same formulary issues (that is, the intriguing ingredients are listed after the preservative) apply here, too, though this formula adds irritating grapefruit juice, which serves no purpose in a sunscreen other than to cause itritation and possibly a photosensitizing reaction.
© $$$ Good Morning Skin Serum ($31 for 0.5 ounce) is a silicone-based serum that contains several plant extracts, some of which can have antioxidant properties for skin and some that can be skin irritants. The teeny amount of mulberry is not enough to inhibit melanin production. |
Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D.
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 Besides, she argued, nutritionists "have long cautioned that children should not drink more than 4 to 12 ounces of juice a day, depending on their age, because it has a lot of sugar and calories without the fiber found in whole fruit and, with the exception of orange and grapefruit juice, not much else."
Indeed, "the bottom line is that the Snapple drinks are basically sugar water. That doesn't make them good for you. That makes them marginally better than soda," adds Dr. Jonny Bowden, author of The 150 Healthiest Foods on Earth. |
Herbert Ross, DC with Keri Brenner, L.Ac.
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 Sanitize all equipment after each use. grapefruit juice may also be used, provided they are blended with some lemon or lime juice.
2. Add the juice of 1 to 2 cloves of garlic and a small amount of ginger juice. To make ginger juice, shred a piece of raw ginger using a grater, then press the shreds with a garlic press to get juice. Alternatively, you can put a 1- to 2-inch piece of ginger root through a juicer.
3. Add 1 tablespoon of high quality, organic, extra-virgin olive oil to the juice. Blend or shake until all of the ingredients are thoroughly combined.
4. |
Jack Challem
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| A recent study found that grapefruit, grapefruit juice, and grapefruit capsules actually helped people to lose weight and improve their insulin function.
Researchers at the Scripps Clinic in San Diego, California, asked ninety-one overweight patients to slightly modify their regular eating habits for twelve weeks. The subjects were asked to eat one-half of a
Avoid Eating Late Dinners
It's all too easy to work late and then eat a big late dinner, but that's bad news in terms of your blood sugar. |
| In addition, avoid all fruit juices except grapefruit juice and avoid fruit smoothies because they are very high in sugars, but they lack the fiber to buffer their absorption.
Practical tip: Fresh berries are often expensive, so if you can't afford them, opt for frozen. Check the package labels to ensure no sugars have been added.
Practical Guideline #5. Eat Healthy Oils and Fats
We still meet people who believe that all fat is bad and that low-fat or zero-fat diets are the healthiest. The truth is that some fats protect against diabetes and weight gain. |
Bill Sardi
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| John's wort and grapefruit juice can decrease levels of drugs by increasing the action of P-glycoprotein. The very introduction of toxic anticancer drugs activates more P-glycoprotein that makes cancer cells even more resistant to treatment. Chemotherapy then proceeds in a backwards fashion. There is little wonder that chemotherapy often fails.
Overcoming cancer resistance
There also may be genetic resistance to anti-cancer drugs. Dr. Robert Nagourney, a hematologist/oncologist, established Rational Therapeutics, Inc. |
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